Interpretable Machine Learning for Population-Level Severe Tooth Loss Prediction: A Two-Axis External Validation

This study presents a survey-weighted, intrinsically interpretable machine learning framework using Explainable Boosting Machines that robustly predicts population-level severe tooth loss across temporal and clinical cohorts while maintaining complete transparency and superior clinical utility compared to black-box alternatives.

LAM, Q. T., Fan, F.-Y., Wang, Y.-L. + 9 more2026-04-05📄 dentistry and oral medicine

Age at Peak Height Velocity: A Systematic Review with Preliminary Quantitative Synthesis of Secular Trends

This preliminary systematic review and quantitative synthesis of two high-quality longitudinal studies indicates that contemporary children reach peak height velocity approximately 0.5 years earlier and with greater velocity than historical cohorts, suggesting a need to adjust the timing of orthodontic growth modification interventions while acknowledging the limited evidence base.

Mahfouz, M., Alzaben, E.2026-03-30📄 dentistry and oral medicine

Integrating Computational Optimization with Antimicrobial Susceptibility Testing: A Particle Swarm Optimization Framework for Enhancing Fluoride Toothpaste Formulations

This study presents a proof-of-concept framework that integrates experimental antimicrobial susceptibility testing of oral *E. coli* with Particle Swarm Optimization and a surrogate Random Forest model to mathematically optimize hypothetical fluoride toothpaste formulations, while explicitly acknowledging that the current results require extensive experimental validation due to limited training data.

Asuai, C., Whiliki, O., Mayor, A. + 7 more2026-03-27📄 dentistry and oral medicine

Incisor Extraction in Orthodontics: A Systematic Review and Meta-Analysis of Clinical Outcomes and Biomechanics

This systematic review and meta-analysis of 20 studies concludes that mandibular incisor extraction offers favorable long-term stability with minimal profile changes, while maxillary incisor movement carries age-dependent risks of palatal bone resorption, and en-masse retraction accelerates space closure without increasing root resorption, though clear aligner accuracy for incisor movement remains limited.

Mahfouz, M., Alzaben, E.2026-03-25📄 dentistry and oral medicine

Miniscrew-Assisted Maxillary Expansion in Children with Compromised First Permanent Molars: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis demonstrates that miniscrew-assisted maxillary expansion offers a predictable, minimally invasive alternative to conventional techniques for children with compromised first permanent molars, achieving superior skeletal expansion with significantly reduced dental tipping and high success rates.

Mahfouz, M., Alzaben, E.2026-03-24📄 dentistry and oral medicine

Smartphones vs DSLR Cameras in Dental Photography: An In Vitro Assessment of Linear Dimensional Shift in the Esthetic Zone

This in vitro study concludes that the Samsung Galaxy S23 Ultra, when used with a stabilization system, offers linear measurement precision comparable to a DSLR camera for dental photography, while the iPhone 15 Pro Max showed minor discrepancies, though the findings' clinical applicability is limited by the controlled experimental setup.

Boontharak, A., Amornsettachai, P., Visuttiwattanakorn, S.2026-03-24📄 dentistry and oral medicine

Temporal Deep Learning for Predicting Periodontitis Progression Using Longitudinal Gingival Crevicular Fluid Protein Profiles

This study develops and validates a compact temporal deep learning framework using longitudinal gingival crevicular fluid protein profiles to accurately predict periodontitis progression and clinical parameters up to two months in advance, outperforming conventional cross-sectional methods and identifying key biomarkers for early intervention.

Zhu, Z. X., Chen, J. J., Teles, F.2026-03-12📄 dentistry and oral medicine

Unusual predominance of Staphylococcus aureus in the salivary microbiome of children with Early Childhood Caries in Kano, Nigeria

This cross-sectional study of children in Kano, Nigeria, reveals an unexpected predominance of *Staphylococcus aureus* over conventional pathogens like *Streptococcus mutans* in the salivary microbiome of those with Early Childhood Caries, suggesting a complex, multifactorial etiology that challenges existing caries paradigms in sub-Saharan Africa.

Okolo, C. C., Amole, T. G.2026-03-06📄 dentistry and oral medicine

Dental teachers perspectives on Extended Reality in dental education: an international survey

This international survey reveals that while dental educators hold positive views on the educational value of Extended Reality for enhancing anatomy understanding and clinical skills, its widespread integration is currently hindered by structural barriers such as high costs, limited technical support, and time constraints.

Bjelovucic, R., de Freitas, B. N., Norholt, S. E. + 3 more2026-03-05📄 dentistry and oral medicine

Efficacy Of Connective Tissue Graft Versus Titanium Papillary Inserts in the Surgical Reconstruction of Interdental Papilla: A Randomized Controlled Clinical Trial

This randomized controlled trial found that while both titanium papillary inserts and connective tissue grafts effectively reconstruct interdental papilla, connective tissue grafts yielded significantly better papilla presence index scores at three months, though titanium inserts remain a viable, less invasive alternative.

Nagar, S. S., Chandra, R. V., Aileni, A. R. + 1 more2026-03-04📄 dentistry and oral medicine

Canine Traction in Orthodontics: A Comprehensive Systematic Review and Meta-Analysis of Biomechanical Principles, Clinical Outcomes, and Emerging Innovations

This comprehensive systematic review and meta-analysis establishes an evidence-based framework for managing mechanically impacted canines through orthodontic traction, demonstrating that while open and closed surgical exposure techniques yield comparable success rates, open exposure offers shorter treatment duration and lower ankylosis risk, whereas closed exposure provides superior patient comfort, all while emphasizing the critical need to differentiate mechanical impaction from primary failure of eruption to guide genetically informed clinical decision-making.

Mahfouz, M., Alzaben, E.2026-03-04📄 dentistry and oral medicine

Association between fluoridated toothpaste use and dental caries in Nigeria: A systematic review and meta-analysis

This systematic review and meta-analysis of 12,719 Nigerian children and adolescents found that while fluoridated toothpaste use is widespread, it is significantly associated with a 16% reduction in dental caries odds primarily in urban and rural settings, with the protective effect varying by residential location and baseline caries severity.

Aborisade, A., Ali, A. M., Amedari, M. + 9 more2026-02-28📄 dentistry and oral medicine

Failure of Tooth Eruption: A Systematic Review and Meta-Analysis Integrating Genetic Etiology, Diagnostic Accuracy, and Clinical Management Outcomes

This systematic review and meta-analysis synthesizes evidence across six domains to establish that primary failure of eruption is frequently linked to PTH1R mutations, orthodontic force should be avoided in confirmed PFE cases, closed surgical exposure for impacted canines offers shorter treatment duration and less pain than open exposure, and early supernumerary removal combined with orthodontics significantly improves eruption success rates.

Mahfouz, M., Alzaben, E.2026-02-23📄 dentistry and oral medicine