This collection explores the evolving landscape of dentistry and oral medicine, focusing on everything from cavity prevention and gum health to complex surgical procedures and systemic links between the mouth and the rest of the body. We translate these critical medical advances into clear, accessible insights so that both specialists and curious readers can understand the latest breakthroughs without getting lost in dense technical language.

Every new preprint in this category originates from medRxiv, where researchers share their findings before formal publication. Gist.Science processes each of these submissions immediately, generating both straightforward plain-language overviews and detailed technical summaries to ensure you get the full picture of the research. Below are the latest papers in dentistry and oral medicine, updated regularly as new studies emerge from the medRxiv server.

Integrating Computational Optimization with Antimicrobial Susceptibility Testing: A Particle Swarm Optimization Framework for Enhancing Fluoride Toothpaste Formulations

This study presents a proof-of-concept framework that integrates experimental antimicrobial susceptibility testing of oral *E. coli* with Particle Swarm Optimization and a surrogate Random Forest model to mathematically optimize hypothetical fluoride toothpaste formulations, while explicitly acknowledging that the current results require extensive experimental validation due to limited training data.

Asuai, C., Whiliki, O., Mayor, A., Victory, D., Imarah, O., Irene, D., Merit, I., Hosni, H., Khan, M. I., Edwin, A. C.2026-03-27📄 dentistry and oral medicine

Smartphones vs DSLR Cameras in Dental Photography: An In Vitro Assessment of Linear Dimensional Shift in the Esthetic Zone

This in vitro study concludes that the Samsung Galaxy S23 Ultra, when used with a stabilization system, offers linear measurement precision comparable to a DSLR camera for dental photography, while the iPhone 15 Pro Max showed minor discrepancies, though the findings' clinical applicability is limited by the controlled experimental setup.

Boontharak, A., Amornsettachai, P., Visuttiwattanakorn, S.2026-03-24📄 dentistry and oral medicine

Unusual predominance of Staphylococcus aureus in the salivary microbiome of children with Early Childhood Caries in Kano, Nigeria

This cross-sectional study of children in Kano, Nigeria, reveals an unexpected predominance of *Staphylococcus aureus* over conventional pathogens like *Streptococcus mutans* in the salivary microbiome of those with Early Childhood Caries, suggesting a complex, multifactorial etiology that challenges existing caries paradigms in sub-Saharan Africa.

Okolo, C. C., Amole, T. G.2026-03-06📄 dentistry and oral medicine

Dental teachers perspectives on Extended Reality in dental education: an international survey

This international survey reveals that while dental educators hold positive views on the educational value of Extended Reality for enhancing anatomy understanding and clinical skills, its widespread integration is currently hindered by structural barriers such as high costs, limited technical support, and time constraints.

Bjelovucic, R., de Freitas, B. N., Norholt, S. E., Taneja, P., Terp Hoybye, M., Pauwels, R.2026-03-05📄 dentistry and oral medicine

Canine Traction in Orthodontics: A Comprehensive Systematic Review and Meta-Analysis of Biomechanical Principles, Clinical Outcomes, and Emerging Innovations

This comprehensive systematic review and meta-analysis establishes an evidence-based framework for managing mechanically impacted canines through orthodontic traction, demonstrating that while open and closed surgical exposure techniques yield comparable success rates, open exposure offers shorter treatment duration and lower ankylosis risk, whereas closed exposure provides superior patient comfort, all while emphasizing the critical need to differentiate mechanical impaction from primary failure of eruption to guide genetically informed clinical decision-making.

Mahfouz, M., Alzaben, E.2026-03-04📄 dentistry and oral medicine

Association between fluoridated toothpaste use and dental caries in Nigeria: A systematic review and meta-analysis

This systematic review and meta-analysis of 12,719 Nigerian children and adolescents found that while fluoridated toothpaste use is widespread, it is significantly associated with a 16% reduction in dental caries odds primarily in urban and rural settings, with the protective effect varying by residential location and baseline caries severity.

Aborisade, A., Ali, A. M., Amedari, M., Salako, A. O., Akinsolu, F. T., Abodunrin, O. R., Ola, O. M., Olagunju, M. T., Eleje, G. U., Lusher, J., Ezechi, O. C., Folayan, M. O.2026-02-28📄 dentistry and oral medicine